Biao Lu Selected Research

EBI-1051

1/2018

Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold.

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Biao Lu Research Topics

Disease

7	Inflammation (Inflammations) 10/2021 - 07/2003
7	Neoplasms (Cancer) 10/2021 - 12/2008
4	Vesicular Stomatitis 01/2021 - 01/2017
4	Acute-Phase Reaction 01/2010 - 10/2006
3	Melanoma (Melanoma, Malignant) 01/2018 - 12/2008
2	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 01/2016
2	Gaucher Disease (Gaucher's Disease) 01/2021 - 11/2019
2	Breast Neoplasms (Breast Cancer) 01/2019 - 02/2003
2	Neuralgia (Stump Neuralgia) 12/2011 - 08/2011
2	Pain (Aches) 12/2011 - 08/2011
1	Pneumonia (Pneumonitis) 01/2022
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 11/2019
1	Rupture 12/2017
1	Atrophy 10/2011
1	Edema (Dropsy) 10/2011
1	Mycoses (Diseases, Fungus) 01/2010
1	Hypertriglyceridemia 01/2010
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2009
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 08/2009
1	Infections 12/2008
1	Ischemic Stroke 10/2006
1	Cerebral Infarction 10/2006
1	Carotid Artery Diseases 03/2006
1	Atherosclerotic Plaque (Atheroma) 03/2006
1	HIV Infections (HIV Infection) 01/2006
1	Coronary Artery Disease (Coronary Atherosclerosis) 11/2005
1	Coronary Stenosis (Coronary Artery Stenosis) 11/2005
1	Pathologic Constriction (Stenosis) 11/2005
1	Viremia 04/2005
1	Barth Syndrome 10/2004
1	Lipodystrophy 07/2004

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2003
4	Glycoproteins (Glycoprotein)IBA 01/2021 - 01/2017
3	Pharmaceutical PreparationsIBA 10/2021 - 12/2008
3	EnzymesIBA 11/2019 - 07/2003
3	Vincristine (Oncovin)FDA LinkGeneric 12/2009 - 12/2008
3	Liposomes (Liposome)IBA 12/2009 - 12/2008
3	CholesterolIBA 08/2009 - 03/2006
3	Tenofovir (Viread)FDA Link 01/2006 - 07/2004
2	Therapeutic UsesIBA 01/2022 - 01/2021
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2021 - 11/2019
2	Green Fluorescent ProteinsIBA 01/2021 - 01/2020
2	EBI-907IBA 02/2016 - 01/2016
2	Capsaicin (Zostrix)FDA Link 12/2011 - 08/2011
2	Messenger RNA (mRNA)IBA 08/2011 - 01/2010
2	Triglycerides (Triacylglycerol)IBA 01/2010 - 12/2008
2	Contrast MediaIBA 03/2006 - 11/2005
2	Lamivudine (Epivir)FDA Link 01/2006 - 04/2005
2	efavirenz (Sustiva)FDA Link 01/2006 - 04/2005
2	Stavudine (Zerit)FDA LinkGeneric 04/2005 - 07/2004
2	RNA (Ribonucleic Acid)IBA 04/2005 - 02/2003
2	LipidsIBA 07/2004 - 07/2004
1	endolysinIBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 10/2021
1	compound 17IBA 10/2021
1	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	polyethylene glycol-recombinant human growth hormoneIBA 01/2021
1	Insulin-Like Growth Factor Binding Protein 2IBA 01/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019
1	Biological ProductsIBA 01/2019
1	HER2 peptide (369-377)IBA 01/2019
1	CytokinesIBA 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2019
1	VaccinesIBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018
1	EBI-1051IBA 01/2018
1	AZD 6244IBA 01/2018
1	VemurafenibIBA 01/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	Anesthetics (Anesthetic Agents)IBA 12/2011
1	Analgesics (Analgesic Drugs)IBA 12/2011
1	Lidocaine (Xylocaine)FDA LinkGeneric 12/2011
1	Prilocaine (Citanest)FDA LinkGeneric 12/2011
1	cardiolipin synthetaseIBA 08/2011
1	Cardiolipins (Cardiolipin)IBA 08/2011
1	LipopolysaccharidesIBA 08/2011
1	Local AnestheticsIBA 08/2011
1	ZymosanIBA 01/2010
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2010
1	Lipoproteins (Lipoprotein)IBA 01/2010
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2010
1	Angiopoietin-Like Protein 4IBA 01/2010
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2009
1	Nonesterified Fatty Acids (NEFA)IBA 12/2008
1	SphingomyelinsIBA 12/2008
1	Phospholipid Transfer ProteinsIBA 09/2007
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2006
1	gadofluorineIBA 03/2006
1	Zidovudine (Retrovir)FDA LinkGeneric 01/2006
1	Emtricitabine (Emtriva)FDA Link 01/2006
1	DNA (Deoxyribonucleic Acid)IBA 04/2005

Therapy/Procedure

1	Surgical Instruments (Clip) 12/2017
1	Duration of Therapy 12/2011
1	Drug Therapy (Chemotherapy) 12/2009
1	Secondary Prevention 10/2006
1	Therapeutics 01/2006
1	Interventional Magnetic Resonance Imaging 11/2005
1	Catheters 11/2005